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Impact of enhancin genes on potency of LdNPV in gypsy moth

Informally Refereed

Abstract

Lymantria dispar nucleopolyhedrovirus (LdNPV) contains two enhancin genes (E1 and E2) encoding proteases that degrade key peritrophic matrix (PM) proteins, thereby promoting infection and mortality by the virus. In a previous study, gypsy moth larvae inoculated with LdNPV in which both E1 and E2 were deleted (double deletion virus) resulted in a non-additive decrease in viral potency compared to potencies of viruses with only 1 of the 2 genes deleted.

Parent Publication

Citation

Hoover, Kelli; McNeil, Jim; Gendron, Alyssa; Slavicek, James. 2011. Impact of enhancin genes on potency of LdNPV in gypsy moth. In: McManus, Katherine A; Gottschalk, Kurt W., eds. 2010. Proceedings. 21st U.S. Department of Agriculture interagency research forum on invasive species 2010; 2010 January 12-15; Annapolis, MD. Gen. Tech. Rep. NRS-P-75. Newtown Square, PA: U.S. Department of Agriculture, Forest Service, Northern Research Station: 93.
https://www.fs.usda.gov/research/treesearch/37613